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Treatments can be highly variable among practitioners, requiring a multidisciplinary approach. Fistulas are classified by anal abcess crohn s relationship to parts of the anal sphincter complex the muscles that allow us to control our stool. Scott Steele : Luca, you brought up a great point there, and one I want to make sure the audience anal abcess crohn s. So just kind of working through that sounds like they're going to come in and get a nice discussion about the different things, give an examination of that perianal region, and then potentially a smaller scope that looks at the inside of the anus. Yet another non-sphincter dividing treatment for anal fistula is the LIFT ligation of the intersphincteric fistula tract procedure. Some series include only patients treated surgically, others include all patients with perianal manifestations such as skin tags and hemorrhoids. Antibiotics often represent the first-line treatment for Crohn's fistulae; their mechanism of action is unknown.